Prolonged Air Leakage After Major Lung Resection

The goal of this prospective randomized controlled trial is to investigate the clinical effects of autologous blood pleurodesis in the treatment of pulmonary air leaks on the first postoperative day following VATS pulmonary resections. Patients will through web-based randomization be randomly assigned into intrapleural instillation of autologous blood (intervention) or standard treatment with ordinary chest drainage (control).

Inclusion Criteria:Patients > 18 years of agePatients willing to give informed consentPatients undergoing VATS lobectomyPatients with a postoperative air leak (> 20ml/min for at least 6 hours).Exclusion Criteria:Patients < 18 years of agePatients not willing to give informed consentTrauma patientsHypotensive patients and patients with a low blood cell count (anemia, thrombocytopenia)