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NCT05632068
Xian-Hua-Cha for Relieving Hyperlipidemia With Obesity
Conditions: Hyperlipidemias, Obesity, Body Fat Disorder
Sex: All
Ages: 20 Years – 75 Years
Healthy volunteers: 1
Phase: PHASE3
Enrollment: 100
Sponsor: Chang Gung Memorial Hospital
Summary
In the past decades, lipid and body fat disorders become a serious global healthcare issue, especially among the obese population.
The aim of this study is to include 100 selected patients with BMI higher than 27 and hyperlipidemia, and a crossover design is used to explore the efficacy of "Xian-Hua-Cha (XHC)" on relieving hyperlipidemia among obese patient.
For this purpose, the changes of patients' body weight, body fat and the metabolic parameter including blood sugar, cholesterol, triglyceride are analyzed in the end of this study.
Eligibility Criteria
Inclusion Criteria:BMI ≧ 27kg/m2Total cholesterol > 200 mg/dL or LDL > 130 mg/dL or triglyceride > 150 mg/dLAge ≧ 20 years and < 75 yearsNo recognition difficultiesWilling to sign inform consent and comply to protocolExclusion Criteria:Pregnant or breast-feeding womenEndocrine disorders (uncontrolled hypo/hyperthyroidism, adrenal gland disorder)Diagnosis of neurologic or psychiatric diseasesLiver or renal dysfunction (AST/ALT higher than 3 times of upper normal limits; eGFR < 60 mL/min/1.73
m2)Acute stress condition (severe infection, receive major surgery in the recent 1 month)Vision, or hearing impairmentWith other clinical trial medicationWith medication for obesity or hyperlipidemia in the recent 1 monthHeavy smoker, alcoholism or substance abuseSevere organ dysfunction: malignancies, autoimmune diseases
Source: ClinicalTrials.gov (NCT05632068). StuddyBuddy aggregates publicly available trial information.