Marginal Bone Level Around Titanium Implants Produced by Additive Manufacture

The aim of this study will be to evaluate the non-inferiority of implants produced by additive manufacture loaded in 30 days when compared with those loaded in 90 days, in relation to marginal bone loss, after 01 (one) year of follow-up

Inclusion Criteria:Patients treated and referred by the Dental Clinic of the School of Dentistry of the University of São Paulo;Individuals over 18 years and under 70 years of age;Good general health;signed Informed Consent Form;Need for rehabilitation with dental implants in areas of mandible or posterior maxilla (premolars and/or molars);bacterial plaque index ≤ 20% (Silness & Loe, 1964);bleeding rate of ≤ 20% (Loe & Silness, 1963);Sufficient alveolar bone volume for an implant of:Length: 8 or 10mmDiameter: 3.5mm, 4. 00mm or 4. 5mmBone quality type I-III;No associated bone regeneration.Exclusion Criteria:Pregnant and lactating women;Uncontrolled diabetes;History of chemotherapy or radiotherapy in the last 5 years;Radiotherapy in areas of the head and neck;Use of immunosuppressants, bisphosphonate or prolonged use of corticosteroids;Smokers;Alcohol or drug abuse;Untreated periodontitis;History of previous bone increase in the implant installation region;Presence of residual roots at the site receiving the implant;Bone density type IVIndividuals with connective tissue disorders or metabolic diseases;Postmenopausal osteoporosis or other systemic diseases that may affect bone metabolism;Need for guided bone regeneration at the time of implant installation.