Dexmedetomidine Versus Gabapentin Premedication on the Emergence Agitation After Rhinoplasty

Conditions: Anesthesia

Sex: All

Ages: 18 Years – 40 Years

Healthy volunteers: 1

Phase: PHASE4

Enrollment: 153

Sponsor: Ain Shams University

Location: Egypt

Summary

To compare the effect of intramuscular dexmedetomidine versus oral gabapentin premedication on the emergence agitation after rhinoplasty.

Eligibility Criteria

Inclusion Criteria:American Society of Anesthesiologists grade I or II.Sex: Both sexes.Age between 18 and 40 years.Patients scheduled for rhinoplasty under general anesthesiaExclusion Criteria:Declining to give written informed consent.History of allergy to the medications used in the study.history of cardiovascular diseases including bradycardia, heart block, and hypertension.History of chest problems including bronchial asthma.Had a history of drug or alcohol abuse.Taking opioids or sedative medications.Inability to communicate with patients to evaluate postoperative pain.Hepatic or renal failure.Psychiatric disorders with antipsychotics or antidepressants.Bleeding disorders, antiplatelets (aspirin, clopidogrel), or anticoagulant (warfarin).

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05626998). StuddyBuddy aggregates publicly available trial information.