Anatomical Evaluation of the APL Tendons in Thumb CMC Joint and Osteoarthritis

Conditions: Thumb Osteoarthritis

Sex: All

Ages: 50 Years – 90 Years

Enrollment: 20

Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Location: Spain

Summary

Certain ligaments in the human body are designed to be a static stabilizer and others to have a sensory function thus remains an unresolved issue.The presence of mechanoreceptors (sensory corpuscles and free nerve endins) in the human knee and ankle ligaments has implies a sensory role of ligaments in providing afferent information, which in turn regulates intrinsic stiffness in the muscles surrounding the joint, contribuiting to dynamic joint stability.The aim of this study is to use immunohistochemical methods to analyze the general innervation and possible existence of sensory corpuscles in the thumb carpometacarpal (CMC) joint. This study can help to know the contribution of the tendon insertions and ligaments in the dynamic thumb CMC joint stability.

Eligibility Criteria

Inclusion Criteria:Specimens: Adults from 50 to 90 years.Exclusion Criteria:Specimens: younger than 50 or older than 90 years.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05626192). StuddyBuddy aggregates publicly available trial information.