← Back to all trials
Recruiting
NCT05623293
Ophthalmologic Outcomes in Patients With Carotid Artery Stenosis
Conditions: Choroid Disease, Carotid Stenosis, Carotid Atherosclerosis, Retinal Disease
Sex: All
Ages: 18 Years – N/A
Enrollment: 40
Sponsor: Universidade do Porto
Location: Portugal
Summary
The retinal vessels have been shown to reflect vascular changes inherent to systemic pathologies, even when no ocular disease is identified.
As such, the eye's vasculature is ableto serve as a window to the vascular health of the human body and a means of assessing systemic endothelial function.
Optical coherence tomography angiography (OCTA) employs optical means to image all the retinal vascular layers and the choroid, providing an extremely detailed image of the microvascular network in a fast, reproducible and totally non-invasive way.
As such, it is currently the best non-invasive way of having an image of human capillaries.
Recently, OCTA has been used to study the retinal vessels' structure and function in several cardiovascular diseases.
As an example of its predictive potential, reduced retinal microvascular density has been associated with the cardiovascular risk profile in patients admitted to the hospital for an acute coronary syndrome.
Recent studies have also shown the retinal microvasculature density to be reduced in patients with carotid artery disease (CAD), namely carotid stenosis, and that endarterectomy increases retinal flow and vessel density.
Eligibility Criteria
Inclusion Criteria:Consecutive carotid stenosisExclusion Criteria:blind patientsRadic stenosis
Source: ClinicalTrials.gov (NCT05623293). StuddyBuddy aggregates publicly available trial information.