Phenotyping of Chronic Pain in Diffused Systemic Scleroderma

The primary objective of the study is to describe the different phenotyping of pain in systemic scleroderma patients and perturbations of mechanisms of the pain.As secondary objectives, the study aims to describe the importances of overall symptoms in alteration of quality of life and conserve the questions which will be associated in a unique questionnaire in order to evaluate the pain, the fatigue and the sleeping disorders in diffused systemic scleroderma patients.

Inclusion Criteria:Patients ≥ 18 years;Patients with diffused SSc according to ACR / EULAR Classification 2013 since at least 3 months;For group pain: pain intensity ≥4 of 11 points of scale (NRS);For group painless: pain intensity on the month before inclusion.Exclusion Criteria:Patients unable to understand french language;Patients no-affiliated to the french social security scheme;Patients under the french AME scheme;Patients under guardianship;Pregnant and breastfeeding patients;Patients with thermoalgesic neuropathy;Articular pain from degenerative diseases (known osteoarthritis);Patients under antidepressant;Temporary discontinuation of analgesics which are not well tolerated.