Burden of Respiratory Syncytial Virus (RSV) in Children in Sweden (BRICS): A Retrospective Study in Sweden

Primary Objective:-Estimate the hospital-associated healthcare resource use (HCRU), and associated costs, of RSV infection in children in comparison to the non-RSV control cohort (general population) and patients with rhinovirus infection.Secondary Objectives:Describe demographic and clinical patient characteristics of RSV infected children.Estimate and compare the incidence of RSV infection and acute respiratory infections (ARIs) in children.Estimate the mortality associated with RSV infection in children.Estimate the social economic burden of RSV infection in children in relation to parents staying home from work to care for their sick child (VAB leave) in comparison to non-RSV control cohort (i.e. parents to children in the general population).Estimate the net days with VAB leave and the compensation disbursed (temporary parental benefit) associated with RSV infection in children.Estimate the indirect costs that can be attributed to VAB leave.Examine the medium- and long-term complications associated with an RSV diagnosis in children in comparison to the non-RSV control chart (general population) and patients with rhinovirus infection.Examine and describe risk factors associated with an RSV infection in childrenEstimate the healthcare resource use (HCRU), and associated costs, of RSV infection in children, for a subset of patients where primary care data is available, in comparison to the non-RSV control cohort (general population).

Inclusion Criteria:•Children (≤5 years of age) with an RSV infection or any acute respiratory infection (ARI) between July 1st 2001 and latest available date, identified in either hospital care, regional primary care or laboratory database.Exclusion Criteria:•There are no exclusion criteria for this study.