A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05)

This study is being done to test the safety and efficacy of the study drug LY3852710 for the treatment of diabetic peripheral neuropathic pain.

Inclusion Criteria:Males and females may participate in this trial.No male contraception is required except in compliance with specific local government study requirements.Women of child bearing potential (WOCBP) and women not of child bearing potential (WNOCBP) may participate in this trial.Contraceptive use by participants should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies.Exclusion Criteria:Have a seizure disorder, history of seizure (other than remote history of childhood febrile seizure), or a condition that would place the participant at increased risk of seizure, such as head injury (for example, skull fracture, cerebral contusion, concussion, or trauma resulting in prolonged unconsciousness), intracranial neoplasm or hemorrhage.Have an eGFR of <30 mL/min/1.73 m2, based on the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula at Day 1 or Day 2.evidence of Hepatitis B virus or Hepatitis C virus.Women who are pregnant or breastfeeding.