A Novel Nomogram to Predict the Postoperative Overall Survival in Gastrointestinal Cancer Patients

This multicenter retrospectively observational cohort study was conducted on participants with histologically confirmed gastric and colorectal cancer who underwent radical surgery in 11 medical centers in China from August 1, 2015, to June 31, 2018. Baseline clinicopathologic data and nutritional status assessments including Nutrition Risk Screening 2002 (NRS 2002) score and Patient-generated Subjective Global Assessment (PG-SGA) rating were collected. Variables will be screened using the least absolute shrinkage and selection operator (LASSO) regression model and Cox regression analysis. Internal and external validations will be performed via the receiver operating curve (ROC), the area under the curve (AUC), the concordance index (C-index), calibration plots, decision curve analysis (DCA), and Five folds cross-validation by 200 times.

Inclusion Criteria:18-80 years oldpostoperative pathological diagnosis of gastric or colorectal adenocarcinomaunderwent radical surgeryTNM stage ranged from stage I to stage IIIExclusion Criteria:NRS 2002 or PG-SGA data was missingpathological diagnosis of gastric stump cancer, cancer in situ, or pin-point cancerin-hospital death or death within 30 days after surgerypreoperative neoadjuvant therapypreoperative endoscopic surgerythe previous history of other malignant tumorspregnancy.