← Back to all trials
Active Not Recruiting
NCT05618236
Sugammadex and Neostigmine in Pediatric Patients
Conditions: Postoperative Vomiting, Postoperative Nausea, Postoperative Delirium
Sex: All
Ages: 5 Years – 12 Years
Enrollment: 130
Sponsor: Marmara University
Location: Turkey
Summary
In this study, it was aimed to compare the use of sugammadex instead of neostigmine + atropine in the reversal of NMB in children undergoing lower abdominal surgery or urogenital surgery, and to compare the rates of postoperative agitation, nausea and vomiting using the FLACC scale, PAED scale and ICC parameters.After the approval of the local ethics committee and written consent from the family, patients who underwent ASA 1, 5-12 years old lower abdomen surgery or urogenital surgery in Pendik Training and Research Hospital will be included in the study.The patients included in the study will be those who were maintained with routine 2-3% sevoflurane inhalation anesthetic and 0.2mcg/kg/min remifentanil intravenous anesthetic, and decurarized with 0.5-1 mg/kg rocuronium.
No drugs other than those administered by the responsible Anesthesiologist during the operation will be administered.The patients included in the study will be divided into 2 groups according to the agent used in decurarization.
There is no condition for the number of patients in the group to be equal.
Group N; neostigmine+atropine, GROUP S; This will be the group of patients decurarized with sugammadex.0-45 days after patients are extubated.
And at the 2nd hour, FLACC Scale (Pain Diagnostic Scale), PAED (Pediatric Anesthesia Recovery Delirium) Scale assessment methods will be compared in terms of pain and agitation.
Nausea and vomiting will be noted as yes/no.
Eligibility Criteria
Inclusion Criteria:After the approval of the local ethics committee and written consent from the family, patients who underwent ASA 1, 5-12 years old lower abdomen surgery or urogenital surgeryExclusion Criteria:who have a history of allergy or anaphylaxis to one of the drugs used children with autism, children with auditory problems, family without consent
Source: ClinicalTrials.gov (NCT05618236). StuddyBuddy aggregates publicly available trial information.