Mirabegron 25 mg for Treatment of Primary Nocturnal Enuresis

Investigators will study the efficacy and safety of mirabegron25 in treatment of primary nocturnal enuresis in comparison to oral desmopressin 120 mcg and behavioral therapy

Inclusion Criteria:primary nocturnal enuresis,negligible daytime wetting,wet at least 4 times over 4 weeksnormal clinical examination with no neurological or urological cause for the enuresisExclusion Criteria:secondary enuresis, polysymptomaticneurologic bladder, neurological disorders,urinary incontinence disordersprevious anti NE drugs.