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Completed NCT05616000

Comparison of Acetyl- L- Carnitine& Folic Acid Versus Coenzyme Q10& Folic Acid on Semen& Hormonal Parameters& Semen Oxidative Status in Patients of Primary Infertility. A Double Blind Randomized Clinical Trial

Conditions: Infertility

Sex: Male
Ages: 20 Years – 45 Years
Healthy volunteers: 1
Phase: PHASE2
Enrollment: 86
Sponsor: Khyber Medical University Peshawar

Location: Pakistan

Summary

The investigators aim is to conduct a double blind randomized clinical trial, to study the effects of Acetyl-L-Carnitine and folic acid versus Coenzyme Q10 and folic acid on Semen and hormonal parameters and semen oxidative stress in patients of Primary infertility. Males diagnosed with Primary Infertility are recruited in the study after fulfilling the inclusion nd exclusion criteria. The investigators propose that Primary infertile men may have altered seminal oxidative status & the combinational therapy may achieve favorable seminal , hormonal& antioxidant levels in men having Primary infertility.

Eligibility Criteria

Inclusion Criteria:Treatment naïve primary male infertile patients with Oligospermia, Asthenozoospermia , Teratozoospermia & NecrozoospermiaAged between 20 - 45 yearsMarried for more than a year with regular intercourse minimum 3/week.Normal female partner with normal menstrual cycleExclusion Criteria:Azoospermic patientsPatients with varicocoeleErectile dysfunctionSecondary infertilityPatients already taking treatment for primary infertility

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05616000). StuddyBuddy aggregates publicly available trial information.