Efficacy of C-PRF vs i-PRF in Thin Gingival Biotype Subjects

Randomized split mouth clinical trials study focused on comparing the efficacy of i-prf versus c-prf injections on gingival thickness and keratinized tissue width in subjects with thin gingival biotype.

Inclusion Criteria:Age ≥18 years and no systemic disease or pregnancy.Non-smoker.Subjects with clinically healthy intact periodontium; bleeding on probing (BOP)<10%, probing pocket depth (PPD)≤3mm, intact periodontium (no probing attachment loss). (Chapple et al., 2018).Four non-adjacent sites of anterior region with thin gingival biotype (GT ≤ 1mm). (Patrick H. et al., 2018).No malocclusion, crowding, filling, missing or supernumerary mandibular anterior teeth.No blood-borne conditions.Any symptoms of recent acute illness e.g., COVID-19.Exclusion CriteriaActive orthodontic treatment.Previous periodontal surgery.Use of blood thinners.Use of any drugs that might lead to gingival enlargement.Attrition.Gingival Recession.Thick gingival biotype.