OptiGon - Optimising Laboratory Assays for Immune Responses to Gonococcus

This is an observational study. Blood collected from otherwise healthy patients presenting with urogenital N.gonorrhoea infection, prior to treatment will be collected to (i) allow the optimisation of assays assessing the immune response to gonococcus and (ii) assess whether N. gonorrhea specific responses can be detected on ELIspot +/- flow cytometry.The investigators plan to recruit up to 30 adults (men and women, aged 18-50 years) who have been diagnosed with urogenital N.gonorrhoea infection at the Sexual Health Clinic at the Oxford University Hospitals NHS Foundation Trust. The investigators will collect blood samples from consenting participants prior to them receiving curative antibiotic treatment.

Inclusion Criteria:Adults (18-50 years) attending Oxford University Hospitals NHS Foundation Trust with untreated urogenital N. gonorrhoea infection confirmed by either:Nucleic acid testMicroscopy of urethral dischargeExclusion Criteria:Have ave already received antimicrobial therapy to treat the urogenital N. gonorrhoea infectionHave not provided written, informed consent.