← Back to all trials
Enrolling By Invitation
NCT05611918
REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study
Conditions: Intra Cerebral Hemorrhage, ICH - Intracerebral Hemorrhage, ICH, Hemorrhage, Stroke, Clot (Blood); Brain, Clot Blood, Cognitive Decline, Cognitive Impairment, Survivorship, Memory Impairment, Motor Activity
Sex: All
Enrollment: 350
Sponsor: Johns Hopkins University
Location: United States
Summary
The investigators propose to perform serial detailed cognitive, motor, behavioral, and blood collection follow-up using longitudinal structured telephone interviews of an anticipated 350 ICH survivors enrolled in Minimally Invasive Surgery Plus Alteplase for Intracerebral Hemorrhage Evacuation (MISTIE) III and ENRICH trials to identify specific cognitive and motor impairment and to perform RNA sequencing to evaluate for evidence of chronic inflammation.
The investigators' expected sample size in 2022 accounts for mortality attrition of 10%/year.
Eligibility Criteria
Inclusion Criteria:Participants in the study must be survivors enrolled in MISTIE III and ENRICH trials at end of each trial's final follow-up (day 365 in MISTIE III and day 180 in ENRICH).
Relatives of known survivors that are found to be deceased since the end of each trial will be interviewed to capture relevant data.Exclusion Criteria:None
Source: ClinicalTrials.gov (NCT05611918). StuddyBuddy aggregates publicly available trial information.
