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Recruiting
NCT05611502
Influence of TMS on Attention Modulation
Conditions: Drinking, Alcohol
Sex: All
Ages: 19 Years – N/A
Healthy volunteers: 1
Phase: NA
Enrollment: 40
Sponsor: Auburn University
Location: United States
Summary
The purpose of this study is to help understand how attention processes influence brain engagement during emotion and social cognition.
The investigators also want to know if these processes are associated with drinking alcohol.Participation includes three study visits of about 2 hours each over approximately a month.
The first visit involves a magnetic resonance imaging (MRI) scan and answering survey questions.
Each of the next two visits will involve a session of transcranial magnetic stimulation (TMS, a non-invasive brain stimulation technique) followed by another MRI scan.People in the Auburn/Opelika area 19 or older are eligible to participate.
People who drink alcohol and people who do not drink or don't drink very much are invited to participate.
Eligibility Criteria
Inclusion Criteria:1. Age 19 or Older2A. (Drinker Group): Reports consuming 4 [if female]/ 5 [if male] or more standard drinks on one occasion at least 2 times a month AND/OR reports consuming more than 7 [if female]/ 14 [if male] standard drinks per week on average2B. (Healthy Volunteer Group): Reports consuming 4 [if female]/ 5 [if male] or more standard drinks on one occasion less than once a month AND reports consuming less than 7 [if female]/ 14 [if male] standard drinks per week on averageExclusion Criteria:MRI ContraindicationsPresence of metal in the body that would make having a 7T MRI unsafe (including facial tattoos)Claustrophobia, such that individual would be unable to stay in the MRI for up to 1 hrHearing loss, including tinnitus, that might be made worse by MRI or TMSTMS ContraindicationsHas ever had a seizure, or has a family history of epilepsyTaking medications or substances that lower the seizure threshold*Implanted devices that are in the head or rely on physiological signalsHistory of neurological disease, such as stroke or brain tumorHead injury with loss of consciousness greater than 30 minutesActively withdrawing from alcoholFamily history of schizophrenia or presence of psychotic symptoms
Source: ClinicalTrials.gov (NCT05611502). StuddyBuddy aggregates publicly available trial information.