Real-time Computer-Aided Detection of Colonic Adenomas With NEC WISE VISION® Endoscopy

This is a prospective, multicenter, randomized study to evaluate the clinical performance of a novel CADe device, WISE VISION® Endoscopy System, in patients undergoing high-definition white light (HDWL) colonoscopy for screening or surveillance of colorectal Cancer (CRC).Eligible subjects who meet the study inclusion/exclusion criteria will be randomized in a 1:1 ratio to undergo colonoscopy :Experimental: CADe colonoscopy procedure with WISE VISION® Endoscopy (CADe Group)Control: Standard Colonoscopy without CADe (Standard Colonoscopy Group)

Inclusion Criteria:Patient is presenting to the endoscopy unit for colon cancer screening or surveillance colonoscopy.Signed Informed ConsentExclusion Criteria:Contraindications to colonoscopyColonoscopy within the previous three (3) yearsHigh-risk indications for colonoscopyAntithrombotic therapy that cannot be stopped, precluding polyp resectionInflammatory bowel diseaseReferred for endoscopic mucosal resection (EMR)Familial adenomatous polyposis syndrome or Serrated Polyposis SyndromePregnant or planning a pregnancy during the study period