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Recruiting
NCT05610410
Peripheral Microvascular Blood Flow in ANOCA
Conditions: ANOCA, HFpEF - Heart Failure With Preserved Ejection Fraction
Sex: All
Ages: 18 Years – N/A
Enrollment: 109
Sponsor: Amsterdam UMC, location VUmc
Location: Netherlands
Summary
An observational cross-sectional cohort study investigating whether peripheral endothelial function assessed using Laser speckle contrast analysis and coronary endothelial function measured with invasive coronary function testing are correlated in patients with angina and no obstructive coronary arteries.
Eligibility Criteria
Inclusion Criteria:Clinical indication for elective invasive coronary function test (ICFT)Suited for one of the study groups:Persistent angina, defined as symptoms of angina; orHFpEF, diagnosed according to the ESC 2021 heart failure guidelinesAbsence of obstructive CAD, documented before inclusion, defined asCCTA - indicative of absence of obstructed coronary arteries, orCAG - <50% diameter stenosis (DS) in the epicardial coronary arteries or (fractional flow reserve (FFR) >0.80 or instant wave free ratio (iFR) >0.89)Exclusion Criteria:Under 18 years of ageUnable or unwilling to undergo ICFT
Source: ClinicalTrials.gov (NCT05610410). StuddyBuddy aggregates publicly available trial information.
