Role of Transcranial Direct Current Stimulation in Appetite and Weight Control

To study the effects of transcranial direct current stimulation (tDCS) on weight and appetite.

Inclusion Criteria:Men and women 18 to 80 years of ageBody mass index > 30 kg/m2Exclusion Criteria:Current participation in any other concurrent clinical trials or previous participation within 30 days before the screening visitPregnancy or premenopausal women who are trying to be pregnantPatients who are incompetent to give consentObesity due to a known secondary cause (Cushing's syndrome, hypothyroidism, etc) or a history of weight loss surgeryHave taken any of the following medications within the past 3 months:phentermine, naltrexone, bupropion, topiratmate, lorcaserin, phendimetrazine, methamphetamine, benzphetamine, diethylpropionAny contraindication to receive transcranial direct current stimulation (tDCS):Personal or family history of seizures, epilepsy or other unexplained loss of consciousness.Current or past history of skin disease or damaged skin on the scalp at the site of stimulation (i.e. eczema, skin with ingrown hairs, acne, razor nicks, wounds that have not healed, recent scar tissue, broken skin, etc.).Prior neurosurgical procedure or radiation.Known diagnosis of brain lesions, such as tumor, stroke or multiple sclerosisImplanted pacemaker, medication pump, vagal stimulator, deep brain stimulator, Transcutaneous Electrical Nerve Stimulation unit, ventriculo-peritoneal shunt or any metallic implant on the head.