Hypoxia and Heart Rate Variability

The purpose of this study is to evaluate how variations in oxygen demands may change heart electrical activity in individuals with and without oxygen dependence.

Healthy ParticipantsInclusion Criteria:• Ability to provide consentExclusion Criteria:BMI > 40 kg/m2Prevalent myocardial infarction, coronary revascularization, heart failure, and strokeUnstable medical conditions that may preclude enrollment in the protocol such as: uncontrolled angina and/or congestive heart failure, uncontrolled blood pressure or resistant hypertension, cancer, and active psychiatric disease (e.g., major depression)Nocturnal HypoxemiaInclusion Criteria:Ability to provide consentChronic respiratory condition resting Sat < 95% off oxygenExclusion Criteria:BMI > 40 kg/m2Prevalent myocardial infarction, coronary revascularization, heart failure, and strokeUnstable medical conditions that may preclude enrollment in the protocol such as: uncontrolled angina and/or congestive heart failure, uncontrolled blood pressure or resistant hypertension, severe chronic obstructive pulmonary disease, cancer, and active psychiatric disease (e.g., major depression)