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Completed
NCT05605171
Posterior Urethrovesical Anastomotic Reconstruction in Comparison to Conventional Urethrovesical Anastomosis
Conditions: Prostate Cancer
Sex: Male
Ages: 18 Years – N/A
Phase: NA
Enrollment: 163
Sponsor: St. Joseph's Healthcare Hamilton
Summary
Urinary incontinence post radical prostatectomy is a well-recognized complication regardless of approach, with a potential negative impact on health-related quality of life.
Although 12-month continence rates range from 85-95% in the literature, few patients are continent in the early postoperative period.
It has been suggested that posterior reconstruction of the Denonvilliers' musculofascial plate, also known as the Rocco stitch, may improve early return to urinary continence, though clinical equipoise remains.
Eligibility Criteria
Inclusion Criteria:Any patient over age 18 (with the ability to give informed consent) with localized prostate cancer (cT1-2, N0, M0).Exclusion Criteria:History of previous prostatic and/or urethral surgeryA known history of a disease or comorbidity that could affect continence, such as insulin-dependent diabetes or urethral stenosisPresence of a urinary catheter preventing preoperative evaluation of continence.
Source: ClinicalTrials.gov (NCT05605171). StuddyBuddy aggregates publicly available trial information.