Lesion Load and Location in Relation to Cognition, Fatigue and Physical Disability in RRMS

In relapsing remitting multiple sclerosis (RRMS) the relationship between cognitive impairment (CI), fatigue and physical disability with white matter lesion load (WM-LL), location among other volumetric measures using automated platforms is still unclear.

Inclusion Criteria:: adult patients of both sexes diagnosed with RRMS according to 2017 McDonald diagnostic criteriaExclusion Criteria:Patients with relapse or steroid administration in the past 30 days were excluded. Patients who have any medical conditions that may affect cognition, and those on psychoactive pharmacotherapy were also excluded.