Investigation of Myocardial Protection Level With Specific Cardioplegia Methods in Cardiac Surgery

Investigating the myocardial effects of cold blood cardioplegia and del nido cardioplegia solution, which are routinely used in clinical practice, will contribute to the studies in the literature on the safety and efficacy of these two methods.For this purpose, patients with coronary artery disease that going to be Coronary Artery Bypass Graft (CABG) surgery will be classified within the scope of the SYNTAX score, the level of exposure to cardioplegia change in proportion to their score will be examined. Also, left ventricular muscle mass will be calculated in patients who will undergo Aortic Valve replacement (AVR) due to Aortic Stenosis, and myocardial protection level proportional to muscle mass will be examined, and cardioplegia efficiency will be compared.

Inclusion Criteria:Subjects planned to have elective coronary artery bypass grafting for coronary artery diseaseSubjects planned to have elective aortic valve surgery due to aortic valve stenosisPatients aged 18-75 yearsBMI of 18.5-30Diabetic and non-diabetic patientsSmokers and non-smokersExclusion Criteria:Subjects under 18 years oldSubjects older than 75 yearsPatients requiring valve surgery with coronary artery bypassPatients requiring aortic valve surgery with pathologies other than aortic valve stenosisPatients requiring mitral or tricuspid valve surgeryPatients undergoing emergency coronary bypassBMI > 30 obese patients