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Completed NCT05601739

Interleukin-1β (rs 1143627 T/C) Gene Polymorphism May Increase the Risk of Developing LDD in Turkish Population

Conditions: Lumbar Disc Degeneration, Low Back Pain, Inflammation

Sex: All
Ages: 18 Years – 60 Years
Healthy volunteers: 1
Enrollment: 94
Sponsor: Yeditepe University

Location: Turkey

Summary

This study aims to show the association between the Interleukin-1β (rs 1143627 T/C) gene polymorphism and the patient's pain level, radiological features, functional disability, and spinal flexibility.

Eligibility Criteria

Inclusion Criteria:Patients with chronic low back pain (over 3 monthsAged 18-60 years oldWith magnetic resonance imaging (MRI) evidencing LDD with Pfirrmann classificationExclusion Criteria:Cauda equina syndromeLumbar spinal stenosisSpinal deformities (scoliosis, kyphosis, spondylolisthesis)Vertebral fracturesInflammatory rheumatic diseasesDiabetic neuropathyPregnancyDrug and alcohol dependencePsychiatric illnessOncologic diseasesWho refuse to sign the consent form and donate a blood sample for analysis of genomic DNA.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05601739). StuddyBuddy aggregates publicly available trial information.