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Completed
NCT05601063
Ascertaining Diagnosis Classification With Elicited Speech
Conditions: Schizophrenia Spectrum and Other Psychotic Disorders, Bipolar and Related Disorders, Depressive Disorder, Anxiety Disorders, Personality Disorders, Attention Deficit Hyperactivity Disorder
Sex: All
Ages: 14 Years – 50 Years
Healthy volunteers: 1
Enrollment: 255
Sponsor: Northwell Health
Location: United States
Summary
Cross-sectional observational study of the relationship between speech patterns and psychiatric symptoms and disorders.
Eligibility Criteria
Inclusion Criteria:Speaks with conversational proficiency with conversational proficiencyCurrent diagnosis in the medical chart of any of the following.
The patient may be in partial but not full remission.
Comorbidity among these disorders and other unlisted disorders is expected and allowable.Schizophrenia-spectrum disorder - schizophrenia, schizophreniform, schizoaffective disorder, delusional disorder, brief psychotic disorder, or unspecified psychotic disorderBipolar spectrum disorder - bipolar I or II disorder, cyclothymia, unspecified or other specified bipolar disorder(Unipolar) Depressive disorder - major depressive disorder, dysthymia, unspecified and other specified depressive disorderAnxiety disorder - obsessive-compulsive disorder, generalized anxiety disorder, panic disorder, post-traumatic stress disorderPersonality disorder - borderline personality disorderAttention-Deficit Hyperactivity DisorderHealthy comparison subjectsAge 14 - 50 yearsHas capacity and willing to sign informed consent; if minor, parent is willing to give consent and child is willing to give assent.Screening will not include a pregnancy test.
Pregnant women will not be screened out of the study because the study procedures are of very low risk overall, and pregnancy does not place the participant or the fetus at any significant risk.Minors will be included in the study because diagnostic ambiguity is prevalent before the age of 18 and this patient group is particularly in need of accurate prognosis and treatment.
Therefore, it is of vital importance that the conclusions of the study be applicable to minors and that they be included among the participants.Exclusion Criteria:Participants with substance-induced disorders or disorders secondary to a general medical condition will not be included as underlying brain changes may be different from "primary" psychiatric disorders.Disorders affecting speech or language, such as aphasia, intellectual disability (IQ<70), or language disorder, or movement disorders affecting speech like tardive dyskinesia, or physical impairments causing significant distortions to speechSerious neurological or endocrine disorder or any medical condition or treatment known to affect the brain and/or language, including but not limited to: neurodegenerative disorders, traumatic brain injury with active symptoms, autism spectrum disorder, encephalitis, epilepsyCognitive or language limitations, or any other factor that would preclude subjects providing informed consent
Source: ClinicalTrials.gov (NCT05601063). StuddyBuddy aggregates publicly available trial information.