Analgesic Effect of Ketamine Vs Ketamine Magnesium Infusion and Their Effect on Postoperative Morphine Consumption

Ketamine and magnesium-ketamine are two analgesics that are being studied for use as adjuvants. They were shown to have anaesthetic and analgesic properties, and as a consequence of this finding, it has been postulated that they may have a role in minimising the requirement for analgesic drugs during the postoperative period. The major objective of the research was to examine the pain-relieving effects of ketamine vs ketamine magnesium infusion, as well as their influence on postoperative morphine consumption following nephrectomy; the secondary goal is to assess hemodynamic effects and pain severity.

Inclusion Criteria:Patients with elective nephrectomyExclusion Criteria:Pregnant womenCases with severe chronic disease as liver cell failures, CHFcases with allergies to ketamine and magnesium sulphatecases with a history of current regular use of (analgesic, anticonvulsant, antidepressant)chronic pain.mental illness.