Comparison of Two Different Types of Platelet Concentrate to Augment Bone Around Immediate Dental Implant

The goal of this clinial trial is to detect Which one of two different platelet concentrate bio-membrane (first or third generation) is better in terms of marginal bone level and bone density around immediate implants in esthetic zone using Cone beam computerized tomography The plasma rich in growth factor or concentrated growth factor? 20 patients with nonrestorable maxillary tooth in the esthetic zone, Subjects will be enrolled The study will use simple randomization to allocate patients into 2 groups, each group will be included 10 patients: Group A: (concentrated growth factor group) ten patients indicated for immediate implant in the maxillary anterior region (class II socket), will be a candidate for immediate implant placement with CGF combined with xenogeneic bone graft Group B: (platelet-rich in growth factor group) Ten patients who indicated immediate implant in the maxillary anterior region (class I or class II socket), will be a candidate for immediate implant placement with PRGF combined with xenogeneic bone graft.

Inclusion Criteria: 1. Selected patients of both sexes are 20-40 years old. 2. Patients are systemically healthy based on questionnaire dental modification of Cornell index. 3. Gingival health according to the new classification system (2017) 4. The recipient site of the implant is free from any pathological conditions. 5. Class II extraction socket according to Chang's classification system 6. Adequate interocclusal space to accommodate the available restorative components. 7. Adequate native/apical bone to achieve primary implant stability. Exclusion Criteria: 1. Pregnant female. 2. Para-functional habits such as bruxism and clenching Patients suffering from periodontitis. 3. Smokers.