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Completed
NCT05511766
Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis
Conditions: Cirrhosis, Hepatic Encephalopathy, Ascites, Varices, SBP - Spontaneous Bacterial Peritonitis
Sex: All
Ages: 18 Years – 75 Years
Healthy volunteers: No
Phase: PHASE2, PHASE3
Enrollment: 150
Sponsor: Tanta University
Location: Tanta University Tanta
Summary
The study aims to compare the potential benefit of allopurinol versus atorvastatin in reducing the risk of developing cirrhosis-related complications, delaying the onset of hepatocellular carcinoma, and improving survival. Furthermore, the study aims to evaluate their impact on parents' related quality of life.
Eligibility Criteria
Inclusion Criteria:
* Inclusion Criteria
* Age 18 to 75 years old
* Both sex
* Adults with cirrhosis in a stable conditions
Exclusion Criteria:
* Exclusion criteria
* Active SBP
* Renal insufficiency (serum creatinine \> 2.0 mg/dl)
* Active GIT hemorrhage
Source: ClinicalTrials.gov (NCT05511766). StuddyBuddy aggregates publicly available trial information.
