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NCT05306600
Onco-Genomas Brasil: Mapping Breast and Prostate Cancer in the Brazilian Public Health System
Conditions: Breast Cancer, Prostate Cancer
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 882
Sponsor: Hospital Moinhos de Vento
Location: Fundação Centro de Controle de Oncologia do Estado do Amazonas Manaus Amazonas
Summary
This project aims to perform complete sequencing of the somatic (tumor) and germline exomes during clinical investigation of cancer patients treated through the Brazilian Unified Health System to generate genomic and phenotypic data for the Brazilian Ministry of Health's National Precision Genomics and Health Program, called Genomas Brasil, as well as to collect data on the population's ancestry.
Eligibility Criteria
Inclusion criteria for breast cancer patients (Arm 1):
* Women aged ≥ 18 years;
* Brazilian nationality;
* After review at the Hospital Moinhos de Vento, confirmed histological diagnosis of breast carcinoma with overexpression of HER2 (classified by immunohistochemistry as 3+ or 2+ with positive in-situ hybridization) or triple-negative (estrogen and progesterone receptors \
Source: ClinicalTrials.gov (NCT05306600). StuddyBuddy aggregates publicly available trial information.
