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Recruiting
NCT05224726
Platelet Rich Plasma for Uterine Scar
Conditions: Cesarean Section Complications, Uterine Bleeding, Pelvic Pain, Menstrual Irregularity
Sex: Female
Ages: 18 Years – 52 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 40
Sponsor: The University of Texas Health Science Center, Houston
Location: Sheba Medical Center Ramat Gan Center
Summary
When vessel wall injury occurs, platelets become activated, releasing more than 30 bioactive proteins, many of which have a fundamental role in hemostasis, inflammation and ultimate wound healing. Platelet-rich plasma (PRP), a modification of fibrin glue made from autologous blood, is being used to deliver growth factors in high concentration to sites requiring wound healing. PRP is obtained from a sample of patients' blood drawn at the time of treatment. As the rate of cesarean deliveries has been rising, long-term adverse sequelae due to uterine scar defects have been increasing. PRP might be a simple preventive treatment that potentially can reduce morbidity following cesarean deliveries.
Eligibility Criteria
Inclusion criteria:
* Women undergoing elective cesarean delivery
* Term pregnancy (≥37 weeks of gestation)
Exclusion criteria:
* Thrombocytopenia (CBC Platelet count \
Source: ClinicalTrials.gov (NCT05224726). StuddyBuddy aggregates publicly available trial information.
