Mapping the Human Appendix Using Single Cell Sequencing

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Enrollment: 5

Sponsor: Bispebjerg Hospital

Summary

The overall purpose of this study is to describe the cellular composition of the human appendix and its gene expression using scRNAseq and scATACseq methods. This will potentially provide is with a complete and detailed map of the appendix´ immunological properties and its role in neuro-endocrine/metabolic functions. Our results will be held up against current knowledge of the appendix and its role in the human body and thus hopefully expand our understanding of this organ and the consequences of its removal by appendectomy.

Eligibility Criteria

Inclusion Criteria: Patients undergoing a right or extended right-hemicolectomy for colon cancer Patients able to read and understand danish Patients able to give informed consent Patients of Scandinavian ethnicity Exclusion Criteria: Previous large bowel resections Suspicion pre or intraoperatively of disease in the appendix Tumour \

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05209061). StuddyBuddy aggregates publicly available trial information.