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Completed NCT05147714

The Relationship Of The Surgical Pleth Index Values With Postoperative Pain Score And Analgesia Consumption

Conditions: Acute Pain, Analgesia

Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: Yes
Enrollment: 52
Sponsor: Istanbul University

Location: Istanbul University Istanbul

Summary

Postoperative pain management has an important role in anesthesia practice. In order to ensure postoperative patient comfort, postoperative rehabilitation should start early and be managed effectively1. It is known that if adequate analgesia is not provided before the patient wakes up, the severity of pain and the total opioid consumption increases. This increased opioid use causes complications such as nausea, vomiting, constipation, increased sleepiness and respiratory depression2. For this reason, the provision of adequate analgesia before the patient is awakened from general anesthesia has an important place in the process. Measurement of pain has different characteristics in patients under sedation or general anesthesia compared to conscious patients. However, since it is not possible for the patient to define pain under general anesthesia, different measurement and evaluation methods are needed. In order to monitor the intraoperative balance between nociception and antinociception, several non-invasive methods with different physiological approaches have been researched and made available for use in the last decade. The aim of these methods is individualize the intraoperative and postoperative opioid dose3. In this context, it has been suggested that the Surgical Pleth Index (SPI) method can be used in the evaluation of the analgesic component of anesthesia.

Eligibility Criteria

Inclusion Criteria: * Aged 18 to 65 years * ASA physical status I-III * Who received craniotomy and intracranial mass excision Exclusion Criteria: * Diagnosed diabetic neuropathy * Using pacemaker * Needing vasoactive agent during the observation * Using ketamine * Using agents such as beta-blockers, beta-agonists, sympatholytic agents, atropine, neostigmine that will affect the sympatho-vagal balance during the observation period * The patients who could not provide sufficient cooperation for scoring were not included in the study.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05147714). StuddyBuddy aggregates publicly available trial information.