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Active Not Recruiting
NCT05112289
A Study to Evaluate White Matter Hyperintensities in Migraine
Conditions: Migraine, Small Vessel Ischemic Disease, Multiple Sclerosis
Sex: Female
Ages: 20 Years – 59 Years
Healthy volunteers: No
Phase: NA
Enrollment: 50
Sponsor: Mayo Clinic
Location: Mayo Clinic in Arizona Phoenix Arizona
Summary
The purpose of this research is to better understand brain white matter hyperintensities (WMH) in women with migraines
Eligibility Criteria
Inclusion Criteria - Migraine (N=20):
* Female only.
* Ages 20-45 years.
* Presence of WMH on MRI.
Exclusion Criteria:
* History of SVI and/or history of MS or other neurological disease other than migraine.
* History of cancer or organ transplantation.
* Contraindication to MRI.
* Pregnancy.
* History of abnormal brain MRI other than WMH.
* Subjects not willing to comply with the study procedures will be removed from the study.
Inclusion Criteria - SVI disease (n=10):
* Female only
* Ages \> 60 years.
* Presence of WMH on MRI.
Exclusion Criteria:
* History of migraine and/or history of MS or other neurological disease other than SVI.
* History of cancer or organ transplantation.
* History of abnormal brain MRI other than WMH.
* Pregnancy.
* History of abnormal brain MRI other than WMH.
* Subjects not willing to comply with the study procedures will be removed from the study.
Inclusion Criteria - MS (n=10):
* Female only.
* Ages 20-45.
* Presence of WMH on MRI.
Exclusion Criteria:
* History of migraine and/or history of SVI or other neurological disease other than MS.
* History of cancer or organ transplantation.
* History of abnormal brain MRI other than WMH.
* Pregnancy.
* History of abnormal brain MRI other than WMH.
* Subjects not willing to comply with the study procedures will be removed from the study.
Source: ClinicalTrials.gov (NCT05112289). StuddyBuddy aggregates publicly available trial information.
