Telemedicine in Early Childhood Constraint Therapy in Cerebral Palsy

This study assesses two active treatments in different sequences and a standard of care group among infants with cerebral palsy.

Inclusion Criteria: * Aged 4 to 13 months, corrected age * Diagnosis of CP or classification of high-risk for CP as determined by published guidelines (\>95% risk of later CP) * Hammersmith Infant Neurological Exam (HINE) arm asymmetry score of greater than or equal to 2 and/or neuroimaging consistent with perinatal involvement * Hand Assessment for Infants (HAI) difference between hands ≥2, with an observable and relative difference in quality or amount of movement between hands, as determined by HAI-certified study therapists and/or a unimanual Bayley score difference between hands \>1 * Parent/legal guardian is able to provide informed consent Exclusion Criteria: * Congenital malformation of the brain or musculoskeletal system (MSK) * Receipt of botulinum toxin to the affected extremity within 3 months of study entry * Any prior long-term hard constraint programs