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Completed
NCT04905225
The Gender Specific Effect on the Results of Ascending Aortic Replacement
Conditions: Ascending Aortic Aneurysm
Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Enrollment: 200
Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences
Location: Tomsk NRMC Tomsk
Summary
The aim of our study is to analyze the early and late results in men and women who underwent ascending aortic replacement in antegrade cerebral perfusion (ACP) with mild-to-moderate hypothermic circulatory arrest. Female gender is associated with poorer outcomes after surgical aorta replacement. Data on gender specific differences after ascending aortic replacement are conflicting.
Eligibility Criteria
Inclusion Criteria:
* Patients with small ascending aortic aneurysm (5.0-5.5 cm)
* Elective procedure
* Able to provide written informed consent
Exclusion Criteria:
* Surgery for acute aortic dissection or emergent operations
* Refusal of surgical treatment
* Oncological disease (high degrees)
* Multiple organ failure
Source: ClinicalTrials.gov (NCT04905225). StuddyBuddy aggregates publicly available trial information.