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Active Not Recruiting NCT04884061

Narrow Band Imaging Bronchoscopy During SARS-CoV2 Infection

Conditions: Covid19, Bronchoscopy, Narrow-band Imaging

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 30
Sponsor: Centre Hospitalier Universitaire, Amiens

Location: CHU Amiens Amiens

Summary

Vascular modifications have been described during SARS-CoV2 infection, especially a dilatation of the bronchial arteries. Within the airway wall, small branches of the bronchial arteries cross the muscle layer to develop a submucosal network. The Narrow Band Imaging technique is used during bronchoscopy to achieve a maximum contrast of vessels and the surrounding mucosa. Therefore, it enables to observe the microvessel structure and its distribution in the bronchial mucosa. The aim of this study is to describe the vasculature pattern of the bronchial tree during infection with SARS-CoV2.

Eligibility Criteria

Inclusion Criteria: * Patients who undergo bronchoscopy with image and/or videos recording of NBI aspect of the proximal bronchial tree (carina, right and left upper lobe). * Patients hospitalized with SARS-CoV2 infection proven by RT-PCR test * patients hospitalized with lower respiratory tract infections unrelated to SARS-CoV2 (RT-PCR negative for SARS-CoV2) * Patients who have had bronchoscopy performed as part of the assessment of a distal pulmonary nodule (RT-PCR negative for SARS-CoV2). Exclusion Criteria: * Patients under legal protection * Patients who refuses the use of his personal medical data

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04884061). StuddyBuddy aggregates publicly available trial information.