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Completed NCT04479514

Preventative Skin Care for Children Undergoing Targeted CNS Tumor Therapy

Conditions: Pediatric Cancer, CNS Tumor, Childhood, Skin Inflammation

Sex: All
Ages: 6 Months – 18 Years
Healthy volunteers: No
Phase: PHASE2
Enrollment: 14
Sponsor: Dana-Farber Cancer Institute

Location: Boston Children's Hospital Boston Massachusetts

Summary

This research study is examining a preventive skin care regimen for children diagnosed with a brain tumor and receiving anti-cancer therapy with a MEK, Pan-RAF, or BRAF inhibitor.

Eligibility Criteria

Inclusion Criteria: * Diagnosed with a brain tumor between ages 6 months old -18 years old and will undergo treatment with at least one of the following: 1. Targeted BRAF inhibitor therapy to treat the brain tumor 2. Targeted MEK inhibitor therapy to treat the brain tumor 3. Targeted pan-RAF inhibitor therapy to treat the brain tumor * Subjects may participate in other studies, including therapeutic trials. * Ability to comply with PSCR including sun protection, gentle skin care and every other day dilute bleach baths. * Ability to understand and/or the willingness of their parent or legally authorized representative to sign a written informed consent document. Exclusion Criteria: * Diagnosed with brain tumor at \> 18 years old * No data in medical records regarding treatment exposures * Treated with a BRAF, MEK or pan-RAF inhibitor in the last three months * Past or present allergic reaction to bleach * Past or present allergic reactions to sunscreen and/or creams, lotions, emollients to be utilized in this study

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04479514). StuddyBuddy aggregates publicly available trial information.