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Completed
NCT04479514
Preventative Skin Care for Children Undergoing Targeted CNS Tumor Therapy
Conditions: Pediatric Cancer, CNS Tumor, Childhood, Skin Inflammation
Sex: All
Ages: 6 Months – 18 Years
Healthy volunteers: No
Phase: PHASE2
Enrollment: 14
Sponsor: Dana-Farber Cancer Institute
Location: Boston Children's Hospital Boston Massachusetts
Summary
This research study is examining a preventive skin care regimen for children diagnosed with a brain tumor and receiving anti-cancer therapy with a MEK, Pan-RAF, or BRAF inhibitor.
Eligibility Criteria
Inclusion Criteria:
* Diagnosed with a brain tumor between ages 6 months old -18 years old and will undergo treatment with at least one of the following:
1. Targeted BRAF inhibitor therapy to treat the brain tumor
2. Targeted MEK inhibitor therapy to treat the brain tumor
3. Targeted pan-RAF inhibitor therapy to treat the brain tumor
* Subjects may participate in other studies, including therapeutic trials.
* Ability to comply with PSCR including sun protection, gentle skin care and every other day dilute bleach baths.
* Ability to understand and/or the willingness of their parent or legally authorized representative to sign a written informed consent document.
Exclusion Criteria:
* Diagnosed with brain tumor at \> 18 years old
* No data in medical records regarding treatment exposures
* Treated with a BRAF, MEK or pan-RAF inhibitor in the last three months
* Past or present allergic reaction to bleach
* Past or present allergic reactions to sunscreen and/or creams, lotions, emollients to be utilized in this study
Source: ClinicalTrials.gov (NCT04479514). StuddyBuddy aggregates publicly available trial information.