← Back to all trials
Completed
NCT04283565
Cost-utility Analysis, Cost-effectiveness Analysis, Budget Impact Analysis
Conditions: Peripheral Arterial Disease
Sex: All
Ages: 50 Years – 90 Years
Healthy volunteers: No
Phase: NA
Enrollment: 614
Sponsor: University Hospital, Tours
Location: BRUEL Saint-Etienne
Summary
Cardiovascular pathologies (CV), the second leading cause of death just behind tumors, are particularly frequent in France and strongly mobilize the resources of the healthcare system (ambulatory and health facility). The French High Authority for Health (HAS) has defined major cardio-vascular risk factors (CVRF): smoking, high blood pressure (hypertension), elevated total cholesterol (TC) or LDL, decreased HDL cholesterol, type II diabetes and age, and predisposing CVRF or discussed: obesity, sedentary lifestyle, menopause, elevation of triglycerides and genetic factors.
Lower-linb peripherial arterial disease (AOMI), even if asymptomatic, involves systemic atherial disease, responsible for mortality irrespective of the presence of CVRF. The prevalence of asymptomatic AOMI is 10 to 20% beyond 55 years old, and the associated mortality is 18 to 30% at 5 years.
Individual screening is achievable by well-conducted clinical evaluation and systematic measurement of the simple, non-invasive Blood Pressure Index (BPI) in all subjects at risk. A BPI\
Eligibility Criteria
CRITERIA FOR INCLUDING PERSONS LENDING TO RESEARCH
• Man over 50 years old and under 80 years old or woman over 60 years old and under 90 years old with at least 2 FRCV including at least 1 major FRCV:
Major LIFs:
* Active or withdrawn smoking for less than 1 year
* Type 2 diabetes, treated or not
Other FRCV:
* Family history: MI, coronary revascularization or sudden death before age 50 with a 1st degree parent
* Dyslipidemia: LDL-cholesterol\> 1.3 g / l and / or HDL-cholesterol \
Source: ClinicalTrials.gov (NCT04283565). StuddyBuddy aggregates publicly available trial information.