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Completed
NCT04258670
Spontaneous Antigenemia in Loiasis
Conditions: Loiasis, Lymphatic Filariasis
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 86
Sponsor: Washington University School of Medicine
Location: Centre for Research on Filariasis and other Tropical Diseases (CRFilMT) Yaoundé
Summary
This prospective study will enroll and follow 60 loiasis patients with high worm burden to monitor the spontaneous release of filarial antigen in peripheral blood. This study will define the cross-reactive antigen profile of persons with spontaneous loiasis antigenemia, and determine whether it varies with time.
Eligibility Criteria
Inclusion Criteria:
* Ability to give informed consent
* Loiasis Mf count \> 20,000 Mf/mL
* Resident of study area
* No evidence of severe or systemic comorbidities
* Consent to storage of blood samples for future study
Exclusion Criteria:
* Subject plans to move from the study area during subsequent 12 months
Source: ClinicalTrials.gov (NCT04258670). StuddyBuddy aggregates publicly available trial information.
