Cognitive and Brain Development in Adolescents With Gilles de la Tourette Syndrome

Sex: All

Ages: 13 Years – 18 Years

Healthy volunteers: Yes

Phase: NA

Enrollment: 132

Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Summary

In children with neurodevelopmental disorders, adolescence is usually associated with a reshaping of the clinical picture and symptomatology. Tourette syndrome (TS) is a paradigmal neurodevelopmental syndrome characterised by involuntary paroxysmal movements (motor tics) and vocalisation (vocal tics) often associated with various psychiatric disorders. The neuronal and cognitive mechanisms associated with TS symptoms improvement during adolescence, or the persistence in adulthood remains unknown, and this is what we aim to address in this study.

Eligibility Criteria

Inclusion Criteria: * Tourette syndrome * Ages 13 - 18 * Acceptance to perform the Brain MRI * Acceptance to perform the cognitive testing * Acceptance to perform the TMS measures Exclusion Criteria: * Learning disability * Incompatibility with MRI procedure (metal body implants, pregnancy)

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04179435). StuddyBuddy aggregates publicly available trial information.