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Completed NCT04072211

Demonstration Project on Health Care Worker Protection Against Hepatitis B in Kalulushi District

Conditions: Hepatitis B Virus, Health Care Associated Infection

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: Yes
Phase: PHASE4
Enrollment: 641
Sponsor: Centre for Infectious Disease Research in Zambia

Location: Kalulushi district all facilities Kalulushi Copperbelt

Summary

Hepatitis B virus (HBV) has infected over one third of the world's population; of these about 350 million go on to be chronic carriers. Infection with HBV can be self-limiting depending on age and immunity status of the infected person. Acute infection with HBV is cleared within six months of initial infection while chronic infection can last longer than six months. HBV can be transmitted perinatally, sexually, horizontally, through direct contact with infectious body fluids or blood, being pricked with an infected needle and injury from instruments contaminated with infectious body fluid or blood. Certain population groups are at higher risk of infection with HBV. Among these populations is that of health care workers (HCWs). In this population, HBV infection can occur through occupational exposure. In fact, the hepatitis B virus is more contagious than human immunodeficiency virus (HIV) during a needle stick injury (30% versus 0.5%). It is therefore imperative that HCWs are highly knowledgeable about HBV and how they can prevent transmission. Protection from HBV infection can be achieved by means of vaccination after which the HBV vaccine has been shown to be 90-100% effective.

Eligibility Criteria

Inclusion Criteria: * Aged ≥18 years * Willing to consent and meet project requirements for training and follow-up. Exclusion Criteria: * Kidney disease or renal failure * Pregnant * History or current neurological condition * Express refusal to consent

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT04072211). StuddyBuddy aggregates publicly available trial information.