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Completed
NCT04064593
Sleep Disordered Breathing (SDB) Prevalence and Cardiovascular Outcomes of Myocardial Infarction (MI) Survivors
Conditions: Acute Myocardial Infarction, Sleep Apnea
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 2007
Sponsor: Assistance Publique - Hôpitaux de Paris
Location: Hôpital Bichat, AP-HP Paris
Summary
The AMISLEEP study is nested in the "FRENCHIE" registry.
The objective is to use routine clinical and polygraphic data to capture SDB/SAS (Sleep Disordered Breathing/Sleep Apnea Syndrome) physiological heterogeneity in relation to clinically relevant cardiovascular outcomes.
Specifically, the investigators hypothesize that unique clusters (phenotypes) of patients could be identified by applying unsupervised learning methods to these data and that the clusters would be differentially associated with risk of adverse cardiovascular outcomes (ACS), TIA, stroke or death). The ultimate goal is to identify patients more at risk that could be included in interventional studies that would test whether SDB/SAS treatment can improve this risk.
Eligibility Criteria
Inclusion Criteria:
* Patient included in FRENCHIE registry (cf. NCT04050956 for FRENCHIE registry's selection criteria)
* Signed consent for AMI-Sleep study
Exclusion Criteria:
* Patient under treatment for SDB/SAS prior to its inclusion in FRENCHIE registry
* Cognitive disorientation and communicative disabilities (left to investigator's discretion) not able to fill-out a questionnaire
* Severe diseases with anticipated mortality less than 6 months
Source: ClinicalTrials.gov (NCT04064593). StuddyBuddy aggregates publicly available trial information.