TFE Renal Cell Carcinoma: A Prospective Registry and Translational Research Initiative

There are limited data regarding the biology and treatment of TFE Renal Cell Carcinoma (TFE RCC). This project provides the infrastructure for acquisition of biological specimens, imaging, and correlative clinical data to facilitate biology studies and characterization of TFE RCC. This registry will collect clinical, demographic, and pathological data, specimens (as available) and imaging from patients with TFE RCC, prospectively. Cases are identified through: 1. Existing clinical and/or cancer registry databases 2. Referrals from clinicians, surgeons, or pathologists 3. Families initiating contact with Registry staff directly

Inclusion Criteria: * All patients of any age with a suspected diagnosis or confirmed diagnosis of a TFE Renal Cell Carcinoma. * Unless the patient is deceased, all patients and/or one parent or legal guardian must provide written informed consent as well as HIPAA/release of information consent. Exclusion Criteria: * Any patient that has not been diagnosed with TFE Renal Cell Carcinoma