Sleep and Circadian Mechanisms of Non-dipping Blood Pressure

Sex: All

Ages: 30 Years – 60 Years

Healthy volunteers: Yes

Enrollment: 30

Sponsor: Oregon Health and Science University

Summary

This study will be the first to distinguish the relative contributions of sleep, circadian and behavioral mechanisms to the non-dipping BP profile in Black adults and will lay the groundwork for optimizing therapies dependent on mechanisms, such as targeting sleep, targeting circadian rhythmicity, or targeting behaviors, and raising the possibility that ideal therapy for hypertension (HTN) may differ by race. This research will ultimately help to improve health and survival in black populations with HTN.

Eligibility Criteria

Inclusion Criteria: * Self-identified Black or White * 'normotensive' (resting systolic blood pressure (SBP) \160/100 mmHg * Smoked within the last year * Regular night work or rotating shift work for the three months prior to the study * Travel across more than three time zones during the three months prior to the study. * Any acute, chronic or debilitating medical conditions, other than mild hypertension (140\

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT03558893). StuddyBuddy aggregates publicly available trial information.