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Active Not Recruiting
NCT03459456
Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)
Conditions: OCD, Obsessive-Compulsive Disorder
Sex: All
Ages: 21 Years – 70 Years
Healthy volunteers: Yes
Enrollment: 27
Sponsor: Baylor College of Medicine
Location: University of Pittsburgh Pittsburgh Pennsylvania
Summary
The investigators propose to synchronize automated measurements of behavior - head, body, and face dynamics, gaze, and vocal prosody - with simultaneous recordings of brain activity in clinically relevant contexts.
Eligibility Criteria
Inclusion Criteria:
OCD subjects:
* The subject has a minimum score of ≥16 on the Y-BOCS;
* If applicable, on a stable pharmacologic regimen;
* Sample will be enriched with OCD subjects having contamination obsessions and handwashing compulsions, and scores on items 9 and 10 of the Y-BOCS reflecting difficulty resisting and controlling compulsions;
Healthy Control Subjects:
* Men and women will be age/gender matched with subjects
* Absence of any psychiatric disorder determined by the MINI\^53 for DSM-5 with the exception of non-impairing specific phobia.
* Low scores on measures of contamination concerns and disgust sensitivity based on Y-BOCS scores below 10 and the Disgust Scale-Revised (total score \
Source: ClinicalTrials.gov (NCT03459456). StuddyBuddy aggregates publicly available trial information.