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Completed
NCT03350308
Prediction of Risk of Hypotension in Hemodialysis
Conditions: Chronical Kidney Disease, Hypotension, Residual Blood Volume, Hemodialysis
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 60
Sponsor: University Hospital, Clermont-Ferrand
Location: CHU Clermont-Ferrand Clermont-Ferrand
Summary
The main objective is to establish a statistical predictive model of the risk of intradialytic hypotension during hemodialysis (HD) or hemodiafiltration (HDF) sessions based on the measurement of residual blood volume and excess extracellular hydration. The secondary objective is to study the impact of dysfunction in the mechanisms of compensation for decreased blood volume (heart disease, neuropathy, drugs) on the risk of intradialytic hypotension.
Eligibility Criteria
Inclusion Criteria:
* 18 years old minimum patients
* Patients with chronic end-stage renal failure
* Patients treated with hemodialysis for at least 3 months, 3 times a week (duration of sessions 3 to 5 hours)
* Patients with at least 2 episodes of intradialytic hypotension in the last month
* Patients without acute events within 3 months prior to inclusion
* Patients affiliated with or receiving social security benefits
Exclusion Criteria:
* Hemoglobin levels outside the limits of measurement (\15g/L)
* Patients whose probable survival does not exceed 6 months
* Patients with progressive acute pathology
* Patient following another research protocol that may influence results
* Patients with psychiatric pathology or cognitive impairments that make them unable to give informed consent
Source: ClinicalTrials.gov (NCT03350308). StuddyBuddy aggregates publicly available trial information.