Precision-exercise-prescription for Lung Cancer Patients Undergoing Surgery: The PEP Study

This is a Phase 3 study aimed at investigating the effects of a personalized exercise program (PEP) in NSCLC patients (stage I, II, IIIa) and secondary lung cancer patients undergoing surgical treatment at the University of Utah and comparing the intervention to the current standard of care (no exercise program).

Inclusion Criteria: * Male or female subject aged ≥ 18 years. * Suspected (per the treating physician) diagnosis of primary lung cancer stage I, II, or IIIa OR secondary lung cancer. * Disease amenable to surgical resection in the opinion of the treating surgeon. * Patients must be able to follow directions and complete questionnaires and exercise diaries in English. * Patients must agree to be randomly assigned to either Intervention or Control Group. Exclusion Criteria: * Deemed ineligible for surgery by the enrolling physician * Abnormalities on screening physical exam judged by study physicians or supervising physical therapist to contraindicate participation in exercise program compliance. * Alcohol or drug abuse as judged by study physicians. * Significant mental or emotional problems that would interfere with study participation will be assessed by the NCCN Distress Thermometer. Any value higher than 7 will trigger further intervention, but ultimately enrollment into the clinical trial will be determined by the enrolling physician.