← Back to all trials
Completed
NCT03133949
Aortitis and Retroperitoneal Fibrosis: Evaluation of Diagnostic Criteria
Conditions: Idiopathic Aortitis, Retroperitoneal Fibrosis
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 210
Sponsor: Centre Hospitalier Universitaire, Amiens
Location: CHU Amiens Picardie Amiens Picardie
Summary
Inflammatory aortitis probably represents a heterogeneous group, and the clinical experience accumulated over the last ten years, shared by the experts of the subject, is that the initial clinical, biological or radiological characteristics should make it possible to differentiate them and dismember the Nosological field.
This will be an essential first step before studying prognosis, risk factors, and therapeutic options.
The search for diagnostic criteria on a large series, similar to the study of classification of vascularites of the ACR in 1990, should make it possible to homogenize the diagnoses for the different teams working on the subject, and to begin work Collaborations, which alone can improve patient care in the future.
Eligibility Criteria
Inclusion Criteria:
* Cases :
* All cases of idiopathic aortitis and retroperitoneal fibrosis followed in participating centers over the past 15 years will be collected.
* Witnesses :
* Group 1: non-idiopathic inflammatory aortitis: all cases of inflammatory aortitis (apart from idiopathic aortites and isolated retroperitoneal fibrosis) followed in the participating centers over the last 15 years will be collected.
* Group 2: subjects with noninflammatory aortic disease, atheromatous type or annulo-ectasitic disease, matched by age and sex with cases. This group will be used to define the differential characteristics between idiopathic aortitis and noninflammatory aortic pathology.
* Group 3: This group will include control subjects aimed at defining radiological normality criteria according to age and sex. As the images are machine-dependent, group 3 controls will be randomly selected from the radiology departments that have performed the scanner or MRI of the corresponding control.
Exclusion Criteria:
* Patients under 18 years of age
Source: ClinicalTrials.gov (NCT03133949). StuddyBuddy aggregates publicly available trial information.