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Completed
NCT03071536
Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation
Conditions: Kidney Function, Kidney Transplant; Complications, Delayed Graft Function
Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 360
Sponsor: King Chulalongkorn Memorial Hospital
Location: King Chulalongkorn Memorial Hospital Bangkok Bangkok
Summary
Furosemide is an old drug that has been used frequently in the postoperative period of kidney transplantation, aiming to achieve adequate urine output. There is no previous study that directly evaluate the urine response to standardized dose of furosemide in the postoperative period. The objective is to measure the urine output after standardized dose of furosemide is delivered, as a biomarker to predict the graft function in perioperative period.
Eligibility Criteria
Inclusion Criteria:
* Deceased donor kidney transplantation at KCMH
* informed consent is accepted
Exclusion Criteria:
* Known allergy to furosemide
* Surgical complication of allograft
* Urgently needed for dialysis (refractory hypervolemia, uremic symptoms, and hyperkalemia)
Source: ClinicalTrials.gov (NCT03071536). StuddyBuddy aggregates publicly available trial information.